Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is sparingly to slightly soluble in methanol and acetone Modafinil (Provigil) is a drug prescribed for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Drug Information on Provigil (modafinil) includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid Uses. In fact, both substances were developed by the same company for the purpose of promoting wakefulness and alertness Modafinil (AKA Provigil) has been around for over 17 years and marketed in over 20 countries to treat disorders such as chronic fatigue. S. 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